Human THBS1 (C-10His)/人THBS1蛋白(HEK293, C-10His) 质控信息
Human THBS1 (C-10His)/人THBS1蛋白(HEK293, C-10His) 生物活性
描述
产品名称：Recombinant Human THBS1 (C-10His)理论分子量：129.2 KDa蛋白种属：Human表达系统：Human Cells蛋白表达区间：Asn19-Pro1170标签：C-10His剂型：干粉纯度：≥85% as determined by reducing SDS-PAGE.储存条件：冻干蛋白应储存在≤-20°C，收到后可稳定保存一年。
溶解后的蛋白溶液可以在2-8°C下保存2-7天。如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。产品背景：Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 contains an N-terminal Laminin G-like globular domain, an extended central region with one vWFC domain, 3 TSP type 1domains, 2 EGF-like domains, and 8 TSP type3 domains, and a globular TSP C-terminal domain. Distinct regions of TSP-1 have been associated with binding to particular ECM or cellular molecules. TSP-1 counteracts the angiogenic, hypotensive, and antithrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 signaling on vascular endothelial cells(EC), and destabilizes adhesive contacts between EC. TSP-1 also plays an important role in wound repair and tissue fibrosis by binding latent TGF-beta and inducing release of the active cytokine from the latency associated peptide (LAP).
Human THBS1 (C-10His)/人THBS1蛋白(HEK293, C-10His) 技术信息
CAS号
N/A
分子量
129.2 KDa
SMILES Code
NONE
别名
重组人THBS1蛋白(HEK293, C-10His)
;Recombinant Human THBS1 (C-10His)
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human THBS1 (C-10His)/人THBS1蛋白(HEK293, C-10His)
|Human THBS1 (C-10His)/人THBS1蛋白(HEK293, C-10His)
| 重组人THBS1蛋白(HEK293, C-10His)
| Recombinant Human THBS1 (C-10His)
| N/A
| Other Target Proteins
| Human THBS1 (C-10His)/人THBS1蛋白(HEK293, C-10His) 纯度/质量文件
| Human THBS1 (C-10His)/人THBS1蛋白(HEK293, C-10His) 生物活性
| Human THBS1 (C-10His)/人THBS1蛋白(HEK293, C-10His) 技术信息
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