货号:A2924851
同义名:
重组人TAC3蛋白(N-6His, E.coli)
/ Recombinant Human TAC3 (N-6His, E.coli); Tachykinin-3
Recombinant Human TAC3 (N-6His, E.coli) 是人源 Tachykinin 3 蛋白,在大肠杆菌中表达,带有 N 端 6×His 标签。该蛋白属于速激肽家族,是一种分泌性蛋白,主要在中枢和外周神经系统中表达,作为神经递质发挥作用,也存在于胎盘外合体滋养层,可能与妊娠期高血压和子痫前期相关,是神经激肽-3受体的配体,其基因突变与正常嗅觉性低促性腺激素性性腺功能减退有关。


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| 描述 | Tachykinin 3 (TAC3) is a secreted protein that belongs to the Tachykinin family. Tachykinins are active peptides that excite neurons and evoke behavioral responses; they are potent vasodilators and secretagogues, and contract many smooth muscles in pregnancy. TAC3 is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. It is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. TAC3 acts as the ligand for the neurokinin-3 receptor, mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. |
| 蛋白种属 | Human |
| 表达系统 | E.coli |
| 标签 | N-6His |
| 蛋白表达区间 | Gln17-Glu121 |
| 蛋白编号 | Q9UHF0 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 13.9 KDa |
| SMILES Code | NONE |
| 别名 | 重组人TAC3蛋白(N-6His, E.coli) ;Recombinant Human TAC3 (N-6His, E.coli); Tachykinin-3; ZNEUROK1; Neurokinin-B; NKB; Neuromedin-K; TAC3; NKNB; UNQ585/PRO1155 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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