Human Siglec-6 (C-Fc, HEK293)/人Siglec-6蛋白(C-Fc, HEK293)
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货号：A2926299同义名：
重组人Siglec-6蛋白(C-Fc, HEK293)
/ Recombinant Human Siglec-6 (C-Fc, HEK293); CD327
Recombinant Human Siglec-6 (C-Fc, HEK293)是人源蛋白，在HEK293人源细胞中表达，带有C端Fc标签。该蛋白又称CD327，属于免疫球蛋白超家族和SIGLEC家族，介导唾液酸依赖性细胞结合，可识别α-2,6-连接的唾液酸，其结合位点可能被同源细胞表面唾液酸的顺式作用遮蔽。主要表达于B细胞和胎盘，可能参与延缓分娩进程，对唾液酸Tn抗原具有特异性。
Human Siglec-6 (C-Fc, HEK293)/人Siglec-6蛋白(C-Fc, HEK293) 化学结构 CAS号：N/A
Human Siglec-6 (C-Fc, HEK293)/人Siglec-6蛋白(C-Fc, HEK293) 3D分子结构 CAS号：N/A
Human Siglec-6 (C-Fc, HEK293)/人Siglec-6蛋白(C-Fc, HEK293) 质控信息
Human Siglec-6 (C-Fc, HEK293)/人Siglec-6蛋白(C-Fc, HEK293) 生物活性
描述
Siglec-6, also known as CD327, belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family. Siglec-6 mediates sialic-acid dependent binding to cells. Siglec-6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Siglec-6 may show increasing expression human labor and following childbirth, it has been speculated that this expression helps to slow the tempo of human labor. Siglec-6 is found on B cells and in placenta, and would seem to have a restricted specificity for the sialyl Tn antigen.
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.5.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human Siglec-6 (C-Fc, HEK293)/人Siglec-6蛋白(C-Fc, HEK293) 技术信息
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