货号:A2925069
同义名:
重组人Serpin B3蛋白(N-6His, E.coli)
/ Recombinant Human Serpin B3 (N-6His, E.coli); Serpin B3
Recombinant Human Serpin B3 (N-6His, E.coli) 是人源丝氨酸蛋白酶抑制剂B3,在大肠杆菌中表达,带有N端6×His标签。该蛋白又称鳞状细胞癌抗原-1(SCCA-1),属于丝氨酸蛋白酶抑制剂超家族中的卵清蛋白相关亚群,参与调控凋亡、炎症、血管生成及胚胎发育,可通过抑制木瓜样半胱氨酸蛋白酶调节肿瘤免疫应答,并抑制UV诱导的凋亡。


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| 描述 | Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). |
| 蛋白种属 | Human |
| 表达系统 | E.coli |
| 标签 | N-6His |
| 蛋白表达区间 | Met1-Pro390 |
| 蛋白编号 | P29508 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 46 KDa |
| SMILES Code | NONE |
| 别名 | 重组人Serpin B3蛋白(N-6His, E.coli) ;Recombinant Human Serpin B3 (N-6His, E.coli); Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; Squamous cell carcinoma antigen 1; T4-A; SCCA1 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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