货号:A2900856
同义名:
重组人STAT3蛋白(E.coli, C-6His)
/ Recombinant Human STAT3 (C-6His); Signal Transducer and Activator of Transcription 3
Recombinant Human STAT3 (C-6His)由大肠杆菌表达系统生产,目标基因编码Met1-Asn175,并在C末端带有6His标签。
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描述 | Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. |
蛋白种属 | Human |
表达系统 | E.coli |
标签 | C-6His |
蛋白表达区间 | Met1-Asn175 |
蛋白编号 | P40763 |
内毒素 | < 1 EU/µg as determined by LAL test. |
剂型 | 干粉 |
剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Trehalose, 50mM NaCl, 0.05% Tween 80, pH 8.0. |
复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
CAS号 | N/A |
分子量 | 21.8 KDa |
SMILES Code | NONE |
别名 | 重组人STAT3蛋白(E.coli, C-6His) ;Recombinant Human STAT3 (C-6His); Signal Transducer and Activator of Transcription 3; Acute-Phase Response Factor; STAT3; APRF |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |