Human SLAMF6 (C-6His, HEK293)/人SLAMF6蛋白(C-6His, HEK293) 质控信息
Human SLAMF6 (C-6His, HEK293)/人SLAMF6蛋白(C-6His, HEK293) 生物活性
描述
SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain, a 21 amino acid transmembrane segment and an 84 amino acid cytoplasmic domain, with two immunoreceptor tyrosine-based switch motifs. SLAMF6 is a homodimer. SLAMF6 can interact with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. Phosphorylation-dependent NTB-A association with SAP is required for full production of IFN-γ by NK cells and independent of EAT-2 binding. It Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. On B cells, NTB-A modulates immunoglobulin class switching and the balance between tolerance and autoimmunity.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human SLAMF6 (C-6His, HEK293)/人SLAMF6蛋白(C-6His, HEK293) 技术信息
CAS号
N/A
分子量
23.4 KDa
SMILES Code
NONE
别名
重组人SLAMF6蛋白(C-6His, HEK293)
;Recombinant Human SLAMF6 (C-6His, HEK293); SLAM Family Member 6; Activating NK Receptor; NK-T-B-Antigen; NTB-A; CD352; SLAMF6; KALI
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human SLAMF6 (C-6His, HEK293)/人SLAMF6蛋白(C-6His, HEK293)
|Human SLAMF6 (C-6His, HEK293)/人SLAMF6蛋白(C-6His, HEK293)
| 重组人SLAMF6蛋白(C-6His, HEK293)
| Recombinant Human SLAMF6 (C-6His, HEK293)
| SLAM Family Member 6
| Activating NK Receptor
| NK-T-B-Antigen
| NTB-A
| CD352
| SLAMF6
| KALI
| N/A
| Macrophage CD Proteins
| Monocyte CD Proteins
| Immune Checkpoint Proteins
| Human SLAMF6 (C-6His, HEK293)/人SLAMF6蛋白(C-6His, HEK293) 纯度/质量文件
| Human SLAMF6 (C-6His, HEK293)/人SLAMF6蛋白(C-6His, HEK293) 生物活性
| Human SLAMF6 (C-6His, HEK293)/人SLAMF6蛋白(C-6His, HEK293) 技术信息
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