S100A7 is a 11-12 kDa member of the S100 family of EF hand calcium binding proteins. Human S100A7 shares 32% amino acid sequence identity with mouse S100A7A, the closest related protein in mouse. It is acetylated at the N-terminus and binds both calcium and zinc ions. S100A7 is up-regulated in keratinocytes of psoriasis and atopic dermatitis lesions, as well as in epithelial cells of the tongue, eye, and female genital tract. Its up-regulation can be induced by bacterial exposure, inflammatory cytokines, or epidermal barrier disruption. S100A7 supports epithelial integrity through killing E. coli by sequestration of zinc and through inducing the up-regulation of tight junction proteins. The interaction of S100A7 with RAGE promotes the migration of immune cells and the infiltration of macrophages into tumor sites.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human S100A7/人S100A7蛋白(E.coli, tag free) 技术信息
CAS号
N/A
分子量
11.5 KDa
SMILES Code
NONE
别名
重组人S100A7蛋白(E.coli, tag free)
;Recombinant Human S100A7; Protein S100-A7; Psoriasin; S100 calcium-binding protein A7; S100A7; PSOR1; S100A7C
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human S100A7/人S100A7蛋白(E.coli, tag free)
|Human S100A7/人S100A7蛋白(E.coli, tag free)
| 重组人S100A7蛋白(E.coli, tag free)
| Recombinant Human S100A7
| Protein S100-A7
| Psoriasin
| S100 calcium-binding protein A7
| S100A7
| PSOR1
| S100A7C
| N/A
| Other Target Proteins
| Human S100A7/人S100A7蛋白(E.coli, tag free) 纯度/质量文件
| Human S100A7/人S100A7蛋白(E.coli, tag free) 生物活性
| Human S100A7/人S100A7蛋白(E.coli, tag free) 技术信息
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