货号:A2924897
同义名:
重组人PPY蛋白(C-6His, HEK293)
/ Recombinant Human PPY (C-6His, HEK293); Pancreatic prohormone
Recombinant Human PPY (C-6His, HEK293) 是人源PPY蛋白,在HEK293人源细胞中表达,带有C端6His标签。该蛋白属于NPY家族,最初以95个氨基酸的前体形式在胰岛中合成,随后被切割为具有生物活性的36个氨基酸激素及一段功能未知的20肽。该活性激素可调节胰腺与胃肠功能,可能参与食欲调控,其血浆水平在食欲增加相关疾病中降低,在神经性厌食症中升高。


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| 描述 | PPY belongs to the NPY family and is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Ala30-Arg88 |
| 蛋白编号 | P01298 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 7.8 KDa |
| SMILES Code | NONE |
| 别名 | 重组人PPY蛋白(C-6His, HEK293) ;Recombinant Human PPY (C-6His, HEK293); Pancreatic prohormone; Pancreatic polypeptide; PNP; PPY |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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