货号:A2925802
同义名:
重组人PPIC蛋白(N-Trx-6His, E.coli)
/ Recombinant Human PPIC (N-Trx-6His, E.coli); Peptidyl-Prolyl Cis-Trans Isomerase C
Recombinant Human PPIC (N-Trx-6His, E.coli) 是人源的重组环孢素相关蛋白C(PPIC),在大肠杆菌中表达,带有N端Trx-6His标签。该蛋白又称环孢素C,是一种肽基脯氨酰顺反异构酶(EC 5.2.1.8),广泛存在于原核与真核生物中,可催化含脯氨酸肽键的顺反异构,影响蛋白质折叠与功能。


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| 描述 | Cyclophilin C is an enzyme (EC 5.2.1.8) found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline. Proline has an unusually conformationally restrained peptide bond due to its cyclic structure with its side chain bonded to its secondary amine nitrogen. Most amino acids have a strong energetic preference for the trans peptide bond conformation due to steric hindrance, but prolines unusual structure stabilizes the cis form so that both isomers are populated under biologically relevant conditions. Proteins with prolyl isomerase activity include cyclophilin, FKBPs, and parvulin, although larger proteins can also contain prolyl isomerase domains. |
| 蛋白种属 | Human |
| 表达系统 | E.coli |
| 标签 | N-Trx-6His |
| 蛋白表达区间 | Lys31-Asp182 |
| 蛋白编号 | P45877 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 液体 |
| 剂型描述 | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 10% Glycerol, pH 7.4. |
| 复溶 | 如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 33.78 KDa |
| SMILES Code | NONE |
| 别名 | 重组人PPIC蛋白(N-Trx-6His, E.coli) ;Recombinant Human PPIC (N-Trx-6His, E.coli); Peptidyl-Prolyl Cis-Trans Isomerase C; PPIase C; Cyclophilin C; Rotamase C; PPIC; CYPC |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |
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