货号:A2925886
同义名:
重组人PDIA6蛋白(C-6His, HEK293)
/ Recombinant Human PDIA6 (C-6His, HEK293); Protein Disulfide-Isomerase A6
Recombinant Human PDIA6 (C-6His, HEK293) 是人源的重组蛋白,在HEK293人源细胞中表达,带有C端6His标签。该蛋白为48.5kDa的蛋白二硫键异构酶A6(PDIA6),属于蛋白二硫键异构酶家族,定位于内质网,催化蛋白质折叠过程中半胱氨酸间二硫键的形成与断裂,具有分子伴侣功能,可抑制错误折叠蛋白聚集,还参与血小板聚集与活化过程。


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| 描述 | Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. The PDIA6 expressed in platelets, its functions as a chaperone that inhibits aggregation of misfolded proteins. PDIA6 is part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1. PDIA6 also plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Leu20-Leu440 |
| 蛋白编号 | Q15084 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 液体 |
| 剂型描述 | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0. |
| 复溶 | 如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 47.2 KDa |
| SMILES Code | NONE |
| 别名 | 重组人PDIA6蛋白(C-6His, HEK293) ;Recombinant Human PDIA6 (C-6His, HEK293); Protein Disulfide-Isomerase A6; Endoplasmic Reticulum Protein 5; ER Protein 5; ERp5; Protein Disulfide Isomerase P5; Thioredoxin Domain-Containing Protein 7; PDIA6; ERP5; P5; TXNDC7 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |
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