Human PD-L2 (C-6His, HEK293)/人PD-L2蛋白(C-6His, HEK293)
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货号：A2924643同义名：
重组人PD-L2蛋白(C-6His, HEK293)
/ Recombinant Human PD-L2 (C-6His, HEK293); Programmed Cell Death 1 Ligand 2
Recombinant Human PD-L2 (C-6His, HEK293)是人源重组PD-L2蛋白，在HEK293细胞中表达，带有C端6×His标签。该蛋白是BTN/MOG家族成员，包含一个Ig样C2型结构域和一个Ig样V型结构域，高表达于心、胎盘、胰腺、肺和肝脏，参与T细胞共刺激信号通路，可独立于PD-1促进T细胞增殖及IFN-γ产生，并通过与PD-1结合抑制T细胞周期进程与细胞因子分泌。
Human PD-L2 (C-6His, HEK293)/人PD-L2蛋白(C-6His, HEK293) 化学结构 CAS号：N/A
Human PD-L2 (C-6His, HEK293)/人PD-L2蛋白(C-6His, HEK293) 3D分子结构 CAS号：N/A
Human PD-L2 (C-6His, HEK293)/人PD-L2蛋白(C-6His, HEK293) 质控信息
Human PD-L2 (C-6His, HEK293)/人PD-L2蛋白(C-6His, HEK293) 生物活性
描述
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human PD-L2 (C-6His, HEK293)/人PD-L2蛋白(C-6His, HEK293) 技术信息
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