Human P-selectin (C-Fc, HEK293)/人P-selectin蛋白(C-Fc, HEK293) 质控信息
Human P-selectin (C-Fc, HEK293)/人P-selectin蛋白(C-Fc, HEK293) 生物活性
描述
P-selectin/CD62P is a single-pass type I membrane protein which is a member of the Selectin family. It consists 768 amino acid (aa). P-selectin is a cell surface glycoprotein expressed by activated platelets and endothelial cells. It induced expression in lung, liver, kidney and heart after endotoxin treatment. Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. it also mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P-selectin interacts with SNX17, PSGL1/SEPL, PODXL2, mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2, and specific tyrosine sulfation on PSGL1.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human P-selectin (C-Fc, HEK293)/人P-selectin蛋白(C-Fc, HEK293) 技术信息
CAS号
N/A
分子量
106.9 KDa
SMILES Code
NONE
别名
重组人P-selectin蛋白(C-Fc, HEK293)
;Recombinant Human P-selectin (C-Fc, HEK293); P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; PADGEM
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human P-selectin (C-Fc, HEK293)/人P-selectin蛋白(C-Fc, HEK293)
|Human P-selectin (C-Fc, HEK293)/人P-selectin蛋白(C-Fc, HEK293)
| 重组人P-selectin蛋白(C-Fc, HEK293)
| Recombinant Human P-selectin (C-Fc, HEK293)
| P-selectin
| CD62 antigen-like family member P
| Granule membrane protein 140
| GMP-140
| Leukocyte-endothelial cell adhesion molecule 3
| LECAM3
| PADGEM
| N/A
| Endothelial cell CD Proteins
| Cell Adhesion Molecules (CAMs)
| Platelet CD Proteins
| Human P-selectin (C-Fc, HEK293)/人P-selectin蛋白(C-Fc, HEK293) 纯度/质量文件
| Human P-selectin (C-Fc, HEK293)/人P-selectin蛋白(C-Fc, HEK293) 生物活性
| Human P-selectin (C-Fc, HEK293)/人P-selectin蛋白(C-Fc, HEK293) 技术信息
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