货号:A2900832
同义名:
重组人Osteocrin蛋白(E.coli, N-6His)
/ Recombinant Human Osteocrin (N-6His); Osteocrin
Recombinant Human Osteocrin (N-6His) 是人源Osteocrin蛋白,在大肠杆菌中表达,带有N端6×His标签。该蛋白是一种分泌性蛋白,主要在骨和肌肉中表达,其前体蛋白经蛋白酶切后生成具有活性的50个氨基酸的C端肽段。人源Osteocrin前体与大鼠和小鼠的同源性分别为77%和78%,可调节成骨细胞分化,也可能作为自分泌和旁分泌因子参与骨骼肌的葡萄糖代谢调控。


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| 描述 | Osteocrin is a secreted protein which is primarily expressed in bone and muscle. It is synthesized as a proprotein that undergoes proteolytic processing to generate a mature 50 amino acid C-terminal active peptide.Human Osteocrin proprotein shares 77% and 78% amino acid sequence identity with the rat and mouse protein, respectively. It appears to modulate osteoblastic differentiation. It could also function as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle. |
| 蛋白种属 | Human |
| 表达系统 | E.coli |
| 标签 | N-6His |
| 蛋白表达区间 | Val28-Gly133 |
| 蛋白编号 | P61366 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 14 KDa |
| SMILES Code | NONE |
| 别名 | 重组人Osteocrin蛋白(E.coli, N-6His) ;Recombinant Human Osteocrin (N-6His); Osteocrin; Musclin; OSTN |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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