Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293)
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货号：A2925605同义名：
重组人Nectin-4蛋白(C-mFc, HEK293)
/ Recombinant Human Nectin-4 (C-mFc, HEK293); PVRL4
Recombinant Human Nectin-4 (C-mFc, HEK293)是人源蛋白，在HEK293人源细胞中表达，带有C端mFc标签。该蛋白为Nectin-4（PVRL4），属于Ig超家族的I型跨膜糖蛋白，含两个Ig样C2型结构域和一个Ig样V型结构域，主要参与细胞间粘附，通过同源及异源相互作用发挥作用，高表达于胎盘、胚胎及乳腺癌组织，其可溶性形式可能由ADAM17介导的蛋白水解产生，与外胚层发育不良并指综合征1型相关。
Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293) 化学结构 CAS号：N/A
Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293) 3D分子结构 CAS号：N/A
Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293) 质控信息
Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293) 生物活性
描述
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.
Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 50 mM NaCl, 5% Sucrose, 5% Mannitol, 0.05% Tween80, pH7.0.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293) 技术信息
CAS号
N/A
分子量
60.7 KDa
SMILES Code
NONE
别名
重组人Nectin-4蛋白(C-mFc, HEK293)
;Recombinant Human Nectin-4 (C-mFc, HEK293); PVRL4; Nectin-4; Ig superfamily receptor LNIR; Poliovirus receptor-related protein 4; PRR4; LNIR
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293)
|Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293)
| 重组人Nectin-4蛋白(C-mFc, HEK293)
| Recombinant Human Nectin-4 (C-mFc, HEK293)
| PVRL4
| Nectin-4
| Ig superfamily receptor LNIR
| Poliovirus receptor-related protein 4
| PRR4
| LNIR
| N/A
| Cell Adhesion Molecules (CAMs)
| Nectin-4/Recombinant Protein
| Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293) 纯度/质量文件
| Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293) 生物活性
| Human Nectin-4 (C-mFc, HEK293)/人Nectin-4蛋白(C-mFc, HEK293) 技术信息
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