货号:A2924450
同义名:
重组人NPTN蛋白(C-6His, HEK293)
/ Recombinant Human NPTN (C-6His, HEK293); Neuroplastin
Recombinant Human NPTN (C-6His, HEK293) 是人源 Neuroplastin 蛋白,在人源细胞中表达,带有 C 端 6×His 标签。该蛋白为 52-57 kDa 的免疫球蛋白超家族成员,包含两个 Ig 样结构域和一个 38 氨基酸的胞质区,可能作为细胞粘附分子参与海马兴奋性突触的长时程增强作用,并通过激活 p38MAPK 和 FGFR1 信号通路调控神经突起生长与突触可塑性。


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| 描述 | Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Gln29-His220 |
| 蛋白编号 | Q9Y639 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 22.69 KDa |
| SMILES Code | NONE |
| 别名 | 重组人NPTN蛋白(C-6His, HEK293) ;Recombinant Human NPTN (C-6His, HEK293); Neuroplastin; Stromal Cell-Derived Receptor 1; SDR-1; NPTN; SDFR1; SDR1 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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