货号:A2924705
同义名:
重组人NKG2A蛋白(N-8His, HEK293)
/ Recombinant Human NKG2A (N-8His, HEK293); NKG2-A/NKG2-B type II integral membrane protein
Recombinant Human NKG2A (N-8His, HEK293) 是人源NKG2A蛋白,在HEK293人源细胞中表达,带有N端8His标签。该蛋白属于II型整合膜蛋白,含一个C型凝集素结构域,属于杀伤细胞凝集素样受体家族,主要在NK细胞中表达,可作为识别HLA-E分子的受体,参与NK细胞及部分细胞毒性T细胞的免疫识别功能。


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| 描述 | NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. NKG2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. NKG2A and NKG2B have been given the designation CD159a in the nomenclature of CD antigens. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | N-8His |
| 蛋白表达区间 | Arg100-Leu233 |
| 蛋白编号 | P26715 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 16.5 KDa |
| SMILES Code | NONE |
| 别名 | 重组人NKG2A蛋白(N-8His, HEK293) ;Recombinant Human NKG2A (N-8His, HEK293); NKG2-A/NKG2-B type II integral membrane protein; CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; CD159a; KLRC1; NKG2A |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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