Human NCAM-1 (C-6His, HEK293)/人NCAM-1蛋白(C-6His, HEK293)
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货号：A2925150同义名：
重组人NCAM-1蛋白(C-6His, HEK293)
/ Recombinant Human NCAM-1 (C-6His, HEK293); CD56
Recombinant Human NCAM-1 (C-6His, HEK293)是人类来源的重组蛋白，在HEK293人源细胞中表达，带有C端6×His标签。该蛋白为神经细胞黏附分子1（NCAM-1），是一种I型跨膜糖蛋白，参与Ca²⁺非依赖性的细胞间及细胞与基质间的相互作用，具有促进神经元黏附、神经突起延伸等功能，并可作为狂犬病毒受体，成人脑内其唾液酸化程度较发育早期降低。
Human NCAM-1 (C-6His, HEK293)/人NCAM-1蛋白(C-6His, HEK293) 化学结构 CAS号：N/A
Human NCAM-1 (C-6His, HEK293)/人NCAM-1蛋白(C-6His, HEK293) 3D分子结构 CAS号：N/A
Human NCAM-1 (C-6His, HEK293)/人NCAM-1蛋白(C-6His, HEK293) 质控信息
Human NCAM-1 (C-6His, HEK293)/人NCAM-1蛋白(C-6His, HEK293) 生物活性
描述
Neural cell adhesion molecule 1 (NCAM-1) is a single-pass type I membrane protein, it belongs to a family of membrane-bound glycoproteins that are involved in Ca2+ independent cell matrix and homophilic or heterophilic cell-cell interactions. NCAM-1 is synthesized as a 761 aa preproprecursor that contains a 19 aa signal sequence, a 722 aa GPI-linked mature region, and a 20 aa C-terminal prosegment. The molecule contains five C-2 type Ig-like domains and two fibronectin type-III domains. NCAM-1 is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Acting as a receptor for rabies virus, NCAM-1 in the adult brain shows a decline of sialylation relative to earlier developmental periods.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human NCAM-1 (C-6His, HEK293)/人NCAM-1蛋白(C-6His, HEK293) 技术信息
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