Human MMP-2 (C-6His)/人MMP-2蛋白(HEK293, C-6His) 质控信息
Human MMP-2 (C-6His)/人MMP-2蛋白(HEK293, C-6His) 生物活性
描述
72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases and tumor invasion. MMP-2 is ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, atherosclerotic plaque rupture, as well as degrading extracellular matrix proteins. MMP-2 can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. MMP-2 cleaves KISS at a Gly-|-Leu bond and appears to have a role in myocardial cell death pathways.
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human MMP-2 (C-6His)/人MMP-2蛋白(HEK293, C-6His) 技术信息
CAS号
N/A
分子量
72 KDa
SMILES Code
NONE
别名
重组人MMP-2蛋白(HEK293, C-6His)
;Recombinant Human MMP-2 (C-6His); 72 kDa Type IV Collagenase; 72 kDa Gelatinase; Gelatinase A; Matrix Metalloproteinase-2; MMP-2; TBE-1; MMP2; CLG4A
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human MMP-2 (C-6His)/人MMP-2蛋白(HEK293, C-6His)
|Human MMP-2 (C-6His)/人MMP-2蛋白(HEK293, C-6His)
| 重组人MMP-2蛋白(HEK293, C-6His)
| Recombinant Human MMP-2 (C-6His)
| 72 kDa Type IV Collagenase
| 72 kDa Gelatinase
| Gelatinase A
| Matrix Metalloproteinase-2
| MMP-2
| TBE-1
| MMP2
| CLG4A
| N/A
| Enzymes & Regulators
| Matrix Metalloproteinases
| Human MMP-2 (C-6His)/人MMP-2蛋白(HEK293, C-6His) 纯度/质量文件
| Human MMP-2 (C-6His)/人MMP-2蛋白(HEK293, C-6His) 生物活性
| Human MMP-2 (C-6His)/人MMP-2蛋白(HEK293, C-6His) 技术信息
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