Human LILRA5 (C-6His, HEK293)/人LILRA5蛋白(C-6His, HEK293) 质控信息
Human LILRA5 (C-6His, HEK293)/人LILRA5蛋白(C-6His, HEK293) 生物活性
描述
Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5（LILRA5）is a member of the leukocyte immunoglobulin-like receptors (LILR), comprise a family of activating and inhibitory type immunoreceptors. LILRA5 consists of a 227 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 10 aa cytoplasmic tail. The ECD contains two Ig-like domains and the transmembrane segment contains a positively charged aspartic acid residue which may mediate its association with the signaling molecule, FcR common gamma chain. LILRA5 is expressed by monocytes, macrophages, and neutrophils. Cross-linking of LILRA5 on monocytes induces the expression of pro-inflammatory cytokines (IL-1beta, IL-6, TNF-alpha) as well as the anti-inflammatory IL-10. It can be detected in tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human LILRA5 (C-6His, HEK293)/人LILRA5蛋白(C-6His, HEK293) 技术信息
CAS号
N/A
分子量
26.1 KDa
SMILES Code
NONE
别名
重组人LILRA5蛋白(C-6His, HEK293)
;Recombinant Human LILRA5 (C-6His, HEK293); Leukocyte immunoglobulin-like receptor subfamily A member 5; CD85 antigen-like family member F; Immunoglobulin-like transcript 11; ILT-11; Leukocyte immunoglobulin-like receptor 9; LIR-9; CD85f; LILRA5; LILRB7
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human LILRA5 (C-6His, HEK293)/人LILRA5蛋白(C-6His, HEK293)
|Human LILRA5 (C-6His, HEK293)/人LILRA5蛋白(C-6His, HEK293)
| 重组人LILRA5蛋白(C-6His, HEK293)
| Recombinant Human LILRA5 (C-6His, HEK293)
| Leukocyte immunoglobulin-like receptor subfamily A member 5
| CD85 antigen-like family member F
| Immunoglobulin-like transcript 11
| ILT-11
| Leukocyte immunoglobulin-like receptor 9
| LIR-9
| CD85f
| LILRA5
| LILRB7
| N/A
| Leukocyte Immunoglobin-like Receptors
| NK Cell CD Proteins
| Human LILRA5 (C-6His, HEK293)/人LILRA5蛋白(C-6His, HEK293) 纯度/质量文件
| Human LILRA5 (C-6His, HEK293)/人LILRA5蛋白(C-6His, HEK293) 生物活性
| Human LILRA5 (C-6His, HEK293)/人LILRA5蛋白(C-6His, HEK293) 技术信息
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