Recombinant Human LAMP1 (C-Fc, HEK293)是人类来源的重组蛋白，在HEK293人源细胞中表达，带有C端Fc标签。该蛋白为溶酶体相关膜糖蛋白1（LAMP1），主要表达于细胞的胞内体-溶酶体膜上，可在溶酶体、胞内体和质膜间穿梭，参与糖链配体向选择素的呈递，并与肿瘤转移相关，有望成为癌症治疗剂及溶酶体贮积症和淋巴细胞脱颗粒的标志物。
Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293) 化学结构 CAS号：N/A
Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293) 3D分子结构 CAS号：N/A
Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293) 质控信息
Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293) 生物活性
描述
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293) 技术信息
CAS号
N/A
分子量
65.5 KDa
SMILES Code
NONE
别名
重组人LAMP1蛋白(C-Fc, HEK293)
;Recombinant Human LAMP1 (C-Fc, HEK293); Lysosome-Associated Membrane Glycoprotein 1; LAMP-1; Lysosome-Associated Membrane Protein 1; CD107 Antigen-Like Family Member A; CD107a; LAMP1
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293)
|Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293)
| 重组人LAMP1蛋白(C-Fc, HEK293)
| Recombinant Human LAMP1 (C-Fc, HEK293)
| Lysosome-Associated Membrane Glycoprotein 1
| LAMP-1
| Lysosome-Associated Membrane Protein 1
| CD107 Antigen-Like Family Member A
| CD107a
| LAMP1
| N/A
| Endothelial cell CD Proteins
| NK Cell CD Proteins
| Stem Cell CD Proteins
| Erythrocyte CD Proteins
| Platelet CD Proteins
| Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293) 纯度/质量文件
| Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293) 生物活性
| Human LAMP1 (C-Fc, HEK293)/人LAMP1蛋白(C-Fc, HEK293) 技术信息
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