Human IgG1 Fc (HEK293)(Asp104-Lys330)
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货号：A2926624同义名：
重组人IgG1 Fc蛋白(Tag free, HEK293)(Asp104-Lys330)
/ Recombinant Human IgG1 Fc (HEK293)(Asp104-Lys330); Immunoglobulin heavy constant gamma 1
Recombinant Human IgG1 Fc (HEK293)(Asp104-Lys330)是人类来源的蛋白，在HEK293人源细胞中表达，为无标签蛋白。该产品为重组人IgG1 Fc片段（Asp104 - Lys330），IgG作为主要参与二次抗体反应的单体免疫球蛋白，是唯一能穿过人类胎盘的免疫球蛋白亚型，可保护机体抵御病原体，该Fc片段在相关免疫过程中发挥重要作用。
Human IgG1 Fc (HEK293)(Asp104-Lys330) 化学结构 CAS号：N/A
Human IgG1 Fc (HEK293)(Asp104-Lys330) 3D分子结构 CAS号：N/A
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human IgG1 Fc (HEK293)(Asp104-Lys330) 技术信息
CAS号
N/A
分子量
23.8 KDa
SMILES Code
NONE
别名
重组人IgG1 Fc蛋白(Tag free, HEK293)(Asp104-Lys330)
;Recombinant Human IgG1 Fc (HEK293)(Asp104-Lys330); Immunoglobulin heavy constant gamma 1; IGHG1
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human IgG1 Fc (HEK293)(Asp104-Lys330)
|Human IgG1 Fc (HEK293)(Asp104-Lys330)
| 重组人IgG1 Fc蛋白(Tag free, HEK293)(Asp104-Lys330)
| Recombinant Human IgG1 Fc (HEK293)(Asp104-Lys330)
| Immunoglobulin heavy constant gamma 1
| IGHG1
| N/A
| Immunoglobulin Fc Region
| Human IgG1 Fc (HEK293)(Asp104-Lys330) 纯度/质量文件
| Human IgG1 Fc (HEK293)(Asp104-Lys330) 生物活性
| Human IgG1 Fc (HEK293)(Asp104-Lys330) 技术信息
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