Recombinant Human INSL3 (C-6His, HEK293)是人类胰岛素样蛋白3，在HEK293人源细胞中表达，带有C端6×His标签。该蛋白属于人源胰岛素家族，是一种分泌蛋白，主要由胎睾及出生后睾丸间质细胞分泌，也存在于黄体、滋养层、胎膜和乳腺中，可能作为LGR8受体的配体，调节引带的生长与分化，从而介导睾丸下降。
Human INSL3 (C-6His, HEK293)/人INSL3蛋白(C-6His, HEK293) 化学结构 CAS号：N/A
Human INSL3 (C-6His, HEK293)/人INSL3蛋白(C-6His, HEK293) 3D分子结构 CAS号：N/A
Human INSL3 (C-6His, HEK293)/人INSL3蛋白(C-6His, HEK293) 质控信息
Human INSL3 (C-6His, HEK293)/人INSL3蛋白(C-6His, HEK293) 生物活性
描述
Insulin-like 3 is a protein that in humans is encoded by the INSL3 gene. It is a secreted protein that belongs to the insulin family. It is expressed in prenatal and postnatal Leydig cells and found as well in the corpus luteum, trophoblast, fetal membranes and breast. It may act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent.It is a ligand for LGR8 receptor.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human INSL3 (C-6His, HEK293)/人INSL3蛋白(C-6His, HEK293) 技术信息
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