货号:A2924721
同义名:
重组人IL-2RG蛋白(C-6His, HEK293)
/ Recombinant Human IL-2RG (C-6His, HEK293); Cytokine receptor common subunit gamma
Recombinant Human IL-2RG (C-6His, HEK293) 是人源IL-2RG蛋白,在HEK293人源细胞中表达,带有C端6His标签。该蛋白包含一个纤维连接蛋白III型结构域,是多种白细胞介素受体(如IL-2、-4、-7和-21受体)的重要信号组分,被称为共同γ链。它与SHB及HTLV-1辅助蛋白p12I相互作用,其缺陷可导致X连锁联合免疫缺陷(XCID)和X连锁重症联合免疫缺陷(XSCID)。


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| 描述 | IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID). |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Leu23-Ala262 |
| 蛋白编号 | P31785 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 15% Trehalose, 6% Mannitol, 0.05% Tween 80, pH8.5. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 29.3 KDa |
| SMILES Code | NONE |
| 别名 | 重组人IL-2RG蛋白(C-6His, HEK293) ;Recombinant Human IL-2RG (C-6His, HEK293); Cytokine receptor common subunit gamma; Interleukin-2 receptor subunit gamma; gammaC; P64; CD132 and IL2RG |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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