Human IL-1R2 (C-Fc, HEK293)/人IL-1R2蛋白(C-Fc, HEK293) 质控信息
Human IL-1R2 (C-Fc, HEK293)/人IL-1R2蛋白(C-Fc, HEK293) 生物活性
描述
Interleukin-1 receptor type 2 (IL1R2) belongs to the interleukin-1 receptor family. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1 receptor type II is a 68 kDa transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and endothelial cells. IL1R2 is non-signaling receptor forIL1A, IL1B and IL1RN, reduces IL1B activities. IL1R2 serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. IL1R2 modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human IL-1R2 (C-Fc, HEK293)/人IL-1R2蛋白(C-Fc, HEK293) 技术信息
CAS号
N/A
分子量
64.5 KDa
SMILES Code
NONE
别名
重组人IL-1R2蛋白(C-Fc, HEK293)
;Recombinant Human IL-1R2 (C-Fc, HEK293); Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human IL-1R2 (C-Fc, HEK293)/人IL-1R2蛋白(C-Fc, HEK293)
|Human IL-1R2 (C-Fc, HEK293)/人IL-1R2蛋白(C-Fc, HEK293)
| 重组人IL-1R2蛋白(C-Fc, HEK293)
| Recombinant Human IL-1R2 (C-Fc, HEK293)
| Interleukin-1 receptor type 2
| IL-1R-2
| IL-1RT-2
| IL-1RT2
| CD121 antigen-like family member B
| CDw121b
| IL-1 type II receptor
| Interleukin-1 receptor beta
| IL-1R-beta
| Interleukin-1 receptor type II
| CD121b
| N/A
| Cytokines and Growth Factor Receptors
| Monocyte CD Proteins
| Interleukin & Receptors
| Human IL-1R2 (C-Fc, HEK293)/人IL-1R2蛋白(C-Fc, HEK293) 纯度/质量文件
| Human IL-1R2 (C-Fc, HEK293)/人IL-1R2蛋白(C-Fc, HEK293) 生物活性
| Human IL-1R2 (C-Fc, HEK293)/人IL-1R2蛋白(C-Fc, HEK293) 技术信息
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