货号:A2924109
同义名:
重组人IL-15RA蛋白(C-Fc, HEK293)
/ Recombinant Human IL-15RA (C-Fc, HEK293); CD215
Recombinant Human IL-15RA (C-Fc, HEK293) 是人源重组蛋白,来自人(Human),在HEK293细胞中表达,带有C-Fc标签。该蛋白为白细胞介素15受体α链(IL-15Rα),是一种跨膜糖蛋白,在免疫发育与功能中发挥多效作用,可维持淋巴细胞稳态,通过结合可溶性IL-15并“转呈”给细胞以响应IL-15,其可溶性形式可作为高亲和力拮抗剂,而IL-15/IL-15Rα复合物则具有强激动活性。


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| 描述 | Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-Fc |
| 蛋白表达区间 | Ile31-Thr172 |
| 蛋白编号 | Q13261-3 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 42.2 KDa |
| SMILES Code | NONE |
| 别名 | 重组人IL-15RA蛋白(C-Fc, HEK293) ;Recombinant Human IL-15RA (C-Fc, HEK293); CD215; IL15RA; CD215 antigen; IL-15 receptor subunit alpha; IL-15RA; IL-15R-alpha; interleukin 15 receptor; alpha; interleukin-15 receptor subunit alpha; MGC104179 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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