货号:A2924049
同义名:
重组人IGF-II蛋白(Tag free, E.coli)
/ Recombinant Human IGF-II (E.coli); Insulin-Like Growth Factor II
Recombinant Human IGF-II (E.coli)是人源蛋白,在大肠杆菌中表达,为无标签蛋白。该蛋白即胰岛素样生长因子II(IGF2),属于胰岛素家族多肽生长因子,参与发育和生长,仅从父系等位基因表达,可能由肝脏分泌并循环于血液,具有促生长活性,能刺激多种细胞包括肌肉、骨骼和软骨组织的增殖与存活,还可能影响胎盘催乳素并参与胎儿发育。


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| 描述 | Insulin-Like Growth Factor II (IGF2) belongs to the insulin family of polypeptide growth factors that is involved in development and growth. Members of this family are structurally homologous to proinsulin, and share higher sequence identity. IGF2 is expressed only from the paternally inherited allele and believed to be secreted by the liver and to circulate in the blood. IGF2 possess growth-promoting activity and can stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF2 is influenced by placental lactogen and may play a role in fetal development. |
| 蛋白种属 | Human |
| 表达系统 | E.coli |
| 标签 | Tag free |
| 蛋白表达区间 | Ala25-Glu91 |
| 蛋白编号 | P01344 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM Glycine-HCl, 4% Sucrose, 4% Mannitol, 0.02% Tween 80 (w/v), pH3.0. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 8.91 KDa |
| SMILES Code | NONE |
| 别名 | 重组人IGF-II蛋白(Tag free, E.coli) ;Recombinant Human IGF-II (E.coli); Insulin-Like Growth Factor II; IGF-II; Somatomedin-A; IGF2; PP1446 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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