Human IFNAR1 (C-6His, HEK293)/人IFNAR1蛋白(C-6His, HEK293) 质控信息
Human IFNAR1 (C-6His, HEK293)/人IFNAR1蛋白(C-6His, HEK293) 生物活性
描述
The Interferon-α/β Receptor 1 (IFN-α/β R1) is a receptor which binds Type I Interferons including Interferon-α and -β. It is a cell surface receptor and heteromeric receptor composed of one chain with two subunits referred to as IFNAR1 and IFNAR2. IFN-α/β R1, in association with IFN-α/β R2, is required for propagating antiviral signal transduction triggered by IFN-α and IFN-β. IFN-α/β R1 interacts very weakly or not at all with type 1 interferons and does not stably interact with IFN-α/β R2. Ligands associate with IFN-α/β R2, and this complex subsequently forms a stable ternary assembly with IFN-α/β R1. IFN-α/β R1 also associates with IFN-γ R2 even in the absence of IFN-γ stimulation. Human IFN-α/β R1 contains a nuclear localization signal in its extracellular domain that is required for receptor translocation to the nucleus following interaction with ligand. Interferon stimulation results in an immunologic response that is especially associated with viruses.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human IFNAR1 (C-6His, HEK293)/人IFNAR1蛋白(C-6His, HEK293) 技术信息
CAS号
N/A
分子量
48.18 KDa
SMILES Code
NONE
别名
重组人IFNAR1蛋白(C-6His, HEK293)
;Recombinant Human IFNAR1 (C-6His, HEK293); Interferon Alpha/Beta Receptor 1; IFN-R-1; IFN-Alpha/Beta Receptor 1; Cytokine Receptor Class-II Member 1; Cytokine Receptor Family 2 Member 1; CRF2-1; Type I Interferon Receptor 1; IFNAR1; IFNAR
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
最近浏览的产品
Tags:
Human IFNAR1 (C-6His, HEK293)/人IFNAR1蛋白(C-6His, HEK293)
|Human IFNAR1 (C-6His, HEK293)/人IFNAR1蛋白(C-6His, HEK293)
| 重组人IFNAR1蛋白(C-6His, HEK293)
| Recombinant Human IFNAR1 (C-6His, HEK293)
| Interferon Alpha/Beta Receptor 1
| IFN-R-1
| IFN-Alpha/Beta Receptor 1
| Cytokine Receptor Class-II Member 1
| Cytokine Receptor Family 2 Member 1
| CRF2-1
| Type I Interferon Receptor 1
| IFNAR1
| IFNAR
| N/A
| Interferon & Receptors
| Human IFNAR1 (C-6His, HEK293)/人IFNAR1蛋白(C-6His, HEK293) 纯度/质量文件
| Human IFNAR1 (C-6His, HEK293)/人IFNAR1蛋白(C-6His, HEK293) 生物活性
| Human IFNAR1 (C-6His, HEK293)/人IFNAR1蛋白(C-6His, HEK293) 技术信息
搜索
