货号:A2924017
同义名:
重组人IFN alpha4蛋白(C-6His, HEK293)
/ Recombinant Human IFN alpha4 (C-6His, HEK293); Interferon alpha-4
Recombinant Human IFN alpha4 (C-6His, HEK293) 是人源干扰素α4重组蛋白,在人源细胞中表达,带有C端6×His标签。该蛋白属于I型干扰素家族,由巨噬细胞分泌,有IFNA4a与IFNA4b两个变体,差异位于编码区第220和410位核苷酸。它能刺激产生蛋白激酶和寡腺苷酸合成酶,介导细胞间通讯,激活免疫系统以清除病原体或肿瘤。


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| 描述 | Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Cys24-Asp189 |
| 蛋白编号 | P05014 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 20.4 KDa |
| SMILES Code | NONE |
| 别名 | 重组人IFN alpha4蛋白(C-6His, HEK293) ;Recombinant Human IFN alpha4 (C-6His, HEK293); Interferon alpha-4; Interferon alpha-4B; Interferon alpha-76; Interferon alpha-M1; IFNA4 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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