货号:A2900804
同义名:
重组人IDO蛋白(E.coli, N-6His)
/ Recombinant Human IDO (N-6His)
Recombinant Human IDO (N-6His)由大肠杆菌表达系统生产,目标基因编码Met1-Gly403,并在N末端带有6His标签。
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描述 | 产品名称:Recombinant Human IDO (N-6His)理论分子量:46.8 KDa蛋白种属:Human表达系统:E.coli蛋白表达区间:Met1-Gly403标签:N-6His剂型:液体纯度:≥95% as determined by reducing SDS-PAGE.储存条件:储存温度≤-70°C,收到后可稳定保存6个月。 储存于≤-70°C,开封后在无菌条件下可稳定保存3个月。 开封后请按照用量分装,尽量减少反复冻融次数。产品背景:Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression. |
CAS号 | N/A |
分子量 | 46.8 KDa |
SMILES Code | NONE |
别名 | 重组人IDO蛋白(E.coli, N-6His) ;Recombinant Human IDO (N-6His) |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |