货号:A2900768
同义名:
重组人HO-1蛋白(E.coli, tag free)
/ Recombinant Human HO-1
Recombinant Human HO-1由大肠杆菌表达系统生产,目标基因编码Met1-Thr261。
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描述 | 产品名称:Recombinant Human HO-1理论分子量:29.86 KDa蛋白种属:Human表达系统:E.coli蛋白表达区间:Met1-Thr261标签:Tag free剂型:液体纯度:≥95% as determined by reducing SDS-PAGE.储存条件:储存温度≤-70°C,收到后可稳定保存6个月。 储存于≤-70°C,开封后在无菌条件下可稳定保存3个月。 开封后请按照用量分装,尽量减少反复冻融次数。产品背景:Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. HO-1 is involved in the regulation of cardiovascular function and response to a variety of stressors. Defects in HO-1 are the cause of Heme Oxygenase 1 deficiency, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues. |
CAS号 | N/A |
分子量 | 29.86 KDa |
SMILES Code | NONE |
别名 | 重组人HO-1蛋白(E.coli, tag free) ;Recombinant Human HO-1 |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |