Human HER3 (C-Fc, HEK293)/人HER3蛋白(C-Fc, HEK293)
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货号：A2925653同义名：
重组人HER3蛋白(C-Fc, HEK293)
/ Recombinant Human HER3 (C-Fc, HEK293); Proto-oncogene-like protein c-ErbB-3
Recombinant Human HER3 (C-Fc, HEK293)是人类来源的重组蛋白，在HEK293人源细胞中表达，带有C-Fc标签。该蛋白为受体酪氨酸蛋白激酶erbB-3，属于表皮生长因子受体（EGFR）家族成员，具有酪氨酸蛋白激酶超家族和EGF受体亚家族特征，含一个蛋白激酶结构域，主要在上皮组织和脑中表达。该膜蛋白具有神经调节蛋白结合域但无活性激酶域，可通过与其它有激酶活性的EGFR家族成员形成异源二聚体发挥作用。
Human HER3 (C-Fc, HEK293)/人HER3蛋白(C-Fc, HEK293) 化学结构 CAS号：N/A
Human HER3 (C-Fc, HEK293)/人HER3蛋白(C-Fc, HEK293) 3D分子结构 CAS号：N/A
Human HER3 (C-Fc, HEK293)/人HER3蛋白(C-Fc, HEK293) 质控信息
Human HER3 (C-Fc, HEK293)/人HER3蛋白(C-Fc, HEK293) 生物活性
描述
Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belongs to the protein kinase superfamily,tyr protein kinase family and EGF receptor subfamily.It contains 1 protein kinase domain and it is expressed in Epithelial tissues and brain. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity.
Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 10% Trehalose, 2% Mannitol, 0.05% Tween 80, pH 9.0.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human HER3 (C-Fc, HEK293)/人HER3蛋白(C-Fc, HEK293) 技术信息
CAS号
N/A
分子量
95.6 KDa
SMILES Code
NONE
别名
重组人HER3蛋白(C-Fc, HEK293)
;Recombinant Human HER3 (C-Fc, HEK293); Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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