FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51（alpha chain) and Beta-2-microglobulin（Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).
Lyophilized from a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, pH7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human FcRn Heterodimer (C-6His, HEK293) 技术信息
CAS号
N/A
分子量
31.2&11.7 KDa
SMILES Code
NONE
别名
重组人FcRn Heterodimer蛋白(C-6His, HEK293)
;Recombinant Human FcRn Heterodimer (C-6His, HEK293); IgG receptor FcRn; Neonatal Fc receptor; FCRN
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
最近浏览的产品
Tags:
Human FcRn Heterodimer (C-6His, HEK293)
|Human FcRn Heterodimer (C-6His, HEK293)
| 重组人FcRn Heterodimer蛋白(C-6His, HEK293)
| Recombinant Human FcRn Heterodimer (C-6His, HEK293)
| IgG receptor FcRn
| Neonatal Fc receptor
| FCRN
| N/A
| FcRn
| Human FcRn Heterodimer (C-6His, HEK293) 纯度/质量文件
| Human FcRn Heterodimer (C-6His, HEK293) 生物活性
| Human FcRn Heterodimer (C-6His, HEK293) 技术信息
搜索
