货号:A2924467
同义名:
重组人FGFRL1蛋白(C-6His, HEK293)
/ Recombinant Human FGFRL1 (C-6His, HEK293); Fibroblast Growth Factor Receptor-Like 1
Recombinant Human FGFRL1 (C-6His, HEK293) 是人源成纤维细胞生长因子受体样蛋白1,在HEK293人源细胞中表达,带有C端6×His标签。该蛋白为单次跨膜I型膜蛋白,属于FGF受体家族,成熟形式包含胞外Ig样结构域、跨膜区及胞内区,主要表达于软骨、肝脏、肾脏、心脏、脑和骨骼肌等组织,具有抑制细胞增殖的作用。


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| 描述 | Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Ala25-Pro378 |
| 蛋白编号 | Q8N441 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 39.9 KDa |
| SMILES Code | NONE |
| 别名 | 重组人FGFRL1蛋白(C-6His, HEK293) ;Recombinant Human FGFRL1 (C-6His, HEK293); Fibroblast Growth Factor Receptor-Like 1; FGF Receptor-Like Protein 1; FGF Homologous Factor Receptor; FGFR-Like Protein; Fibroblast Growth Factor Receptor 5; FGFR-5; FGFRL1; FGFR5; FHFR |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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