Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293)
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货号：A2924676同义名：
重组人Ephrin-A1蛋白(C-6His, HEK293)
/ Recombinant Human Ephrin-A1 (C-6His, HEK293); Ephrin-A1
Recombinant Human Ephrin-A1 (C-6His, HEK293)是人源蛋白，在HEK293人源细胞中表达，带有C端6×His标签。该蛋白属于A型Ephrin家族，作为A型Eph受体酪氨酸激酶家族的配体，可被TNF和IL1B诱导表达，其表达水平在原发性胶质瘤组织中较正常组织下调，可溶性单体形式存在于多形性胶质母细胞瘤及乳腺癌细胞中，参与血管生成和肿瘤新生血管形成。
Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293) 化学结构 CAS号：N/A
Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293) 3D分子结构 CAS号：N/A
Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293) 质控信息
Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293) 生物活性
描述
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 4% Trehalose, 4% Mannitol, 0.02% Tween 80, pH 8.0.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293) 技术信息
CAS号
N/A
分子量
20.39 KDa
SMILES Code
NONE
别名
重组人Ephrin-A1蛋白(C-6His, HEK293)
;Recombinant Human Ephrin-A1 (C-6His, HEK293); Ephrin-A1; EPH-Related Receptor Tyrosine Kinase Ligand 1; LERK-1; Immediate Early Response Protein B61; Tumor Necrosis Factor Alpha-Induced Protein 4; TNF Alpha-Induced Protein 4; EFNA1; EPLG1; LERK1; TNFAIP4
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293)
|Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293)
| 重组人Ephrin-A1蛋白(C-6His, HEK293)
| Recombinant Human Ephrin-A1 (C-6His, HEK293)
| Ephrin-A1
| EPH-Related Receptor Tyrosine Kinase Ligand 1
| LERK-1
| Immediate Early Response Protein B61
| Tumor Necrosis Factor Alpha-Induced Protein 4
| TNF Alpha-Induced Protein 4
| EFNA1
| EPLG1
| LERK1
| TNFAIP4
| N/A
| Ephrin/Eph Family
| Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293) 纯度/质量文件
| Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293) 生物活性
| Human Ephrin-A1 (C-6His, HEK293)/人Ephrin-A1蛋白(C-6His, HEK293) 技术信息
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