Human EpCAM (C-Fc, HEK293)/人EpCAM蛋白(C-Fc, HEK293) 质控信息
Human EpCAM (C-Fc, HEK293)/人EpCAM蛋白(C-Fc, HEK293) 生物活性
描述
Epithelial Cell Adhesion Molecule (EpCAM) is a signal type I transmembrane glycoprotein that belongs to the EPCAM family. EpCAM is composed of an extracellular domain with one thyroglobulin type-1 domain, a transmembrane domain and a cytoplasmic domain. EpCAM is found on the surface of adenocarcinoma, but not on mesodermal or neural cell membranes. The EpCAM molecule has been shown to function as a homophilic Ca2+ independent adhesion molecule. It may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium as an immunological barrier providing the first line of defense against infection. Defects in EPCAM are a cause of hereditary non-polyposis colorectal cancer type 8 (HNPCC8) and diarrhea type 5 (DIAR5). EpCAM plays a role in embryonic stem cells proliferation and differentiation; it up-regulates the expression of FABP5, MYC and Cyclin A and Cyclin E. It is highly and selectively expressed by undifferentiated embryonic stem cells.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human EpCAM (C-Fc, HEK293)/人EpCAM蛋白(C-Fc, HEK293) 技术信息
CAS号
N/A
分子量
54.5 KDa
SMILES Code
NONE
别名
重组人EpCAM蛋白(C-Fc, HEK293)
;Recombinant Human EpCAM (C-Fc, HEK293); Epithelial Cell Adhesion Molecule; Ep-CAM; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; Epithelial Cell Surface Antigen; Epithelial Glycoprotein 314; EGP314; Major Gastrointestinal Tumor-Associated Protein GA733-2; Tumor-Associated Calcium Signal Transducer 1; CD326; EPCAM; GA733-2; TROP1
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
最近浏览的产品
Tags:
Human EpCAM (C-Fc, HEK293)/人EpCAM蛋白(C-Fc, HEK293)
|Human EpCAM (C-Fc, HEK293)/人EpCAM蛋白(C-Fc, HEK293)
| 重组人EpCAM蛋白(C-Fc, HEK293)
| Recombinant Human EpCAM (C-Fc, HEK293)
| Epithelial Cell Adhesion Molecule
| Ep-CAM
| Adenocarcinoma-Associated Antigen
| Cell Surface Glycoprotein Trop-1
| Epithelial Cell Surface Antigen
| Epithelial Glycoprotein 314
| EGP314
| Major Gastrointestinal Tumor-Associated Protein GA733-2
| Tumor-Associated Calcium Signal Transducer 1
| CD326
| EPCAM
| GA733-2
| TROP1
| N/A
| Dendritic Cell CD Proteins
| Epithelial cell CD Proteins
| Stem Cell CD Proteins
| CAR-T related Proteins
| Human EpCAM (C-Fc, HEK293)/人EpCAM蛋白(C-Fc, HEK293) 纯度/质量文件
| Human EpCAM (C-Fc, HEK293)/人EpCAM蛋白(C-Fc, HEK293) 生物活性
| Human EpCAM (C-Fc, HEK293)/人EpCAM蛋白(C-Fc, HEK293) 技术信息
搜索
