Human DKK-1 (C-6His)/人DKK-1蛋白(HEK293, C-6His) 质控信息
Human DKK-1 (C-6His)/人DKK-1蛋白(HEK293, C-6His) 生物活性
描述
Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human DKK-1 (C-6His)/人DKK-1蛋白(HEK293, C-6His) 技术信息
CAS号
N/A
分子量
26.6 KDa
SMILES Code
NONE
别名
重组人DKK-1蛋白(HEK293, C-6His)
;Recombinant Human DKK-1 (C-6His); Dickkopf-related protein 1; Dickkopf-1; Dkk-1
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human DKK-1 (C-6His)/人DKK-1蛋白(HEK293, C-6His)
|Human DKK-1 (C-6His)/人DKK-1蛋白(HEK293, C-6His)
| 重组人DKK-1蛋白(HEK293, C-6His)
| Recombinant Human DKK-1 (C-6His)
| Dickkopf-related protein 1
| Dickkopf-1
| Dkk-1
| N/A
| Other Target Proteins
| Human DKK-1 (C-6His)/人DKK-1蛋白(HEK293, C-6His) 纯度/质量文件
| Human DKK-1 (C-6His)/人DKK-1蛋白(HEK293, C-6His) 生物活性
| Human DKK-1 (C-6His)/人DKK-1蛋白(HEK293, C-6His) 技术信息
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