Recombinant Human CXCL9 (C-6His) 是人源重组蛋白，在人源细胞中表达，带有C端6×His标签。该蛋白属于趋化因子CXC家族，由干扰素刺激的单核细胞、巨噬细胞和内皮细胞分泌，通过与趋化因子受体CXCR3相互作用发挥趋化功能，能够吸引Th1细胞，参与免疫与炎症相关细胞的生长、活化和迁移，并具有抑制肿瘤生长的作用，与CXCL10和CXCL11密切相关。
Human CXCL9 (C-6His)/人CXCL9蛋白(HEK293, C-6His) 化学结构 CAS号：N/A
Human CXCL9 (C-6His)/人CXCL9蛋白(HEK293, C-6His) 3D分子结构 CAS号：N/A
Human CXCL9 (C-6His)/人CXCL9蛋白(HEK293, C-6His) 质控信息
Human CXCL9 (C-6His)/人CXCL9蛋白(HEK293, C-6His) 生物活性
描述
Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions by interacting with the chemokine receptor CXCR3. CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumour growth inhibition. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human CXCL9 (C-6His)/人CXCL9蛋白(HEK293, C-6His) 技术信息
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