货号:A2900728
同义名:
重组人CXCL5蛋白(E.coli, tag free)
/ Recombinant Human CXCL5; C-X-C Motif Chemokine 5
Recombinant Human CXCL5是人源重组蛋白,在大肠杆菌中表达,为无标签形式。该蛋白属于C-X-C趋化因子家族,可裂解为ENA-78(8-78)和ENA-78(9-78),具有更强的中性粒细胞趋化活性,主要通过与CXCR2相互作用发挥作用,其上调与多种癌症的血管生成、肿瘤生长及转移相关。


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| 描述 | C-X-C Motif Chemokine 5 (CXCL5) is a member of the Intercrine Alpha (Chemokine CXC) family. CXCL5 can be cleaved into the following two chains, ENA-78 (8-78) and ENA-78 (9-78). In vitro, ENA-78(8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. CXCL5 is a secreted protein and exercises the functions primarily through interactions with CXCR2. The upregulation of CXCL5 contributes to increased vascularization, tumor grown, and metastasis in many cancers. |
| 蛋白种属 | Human |
| 表达系统 | E.coli |
| 标签 | Tag free |
| 蛋白表达区间 | Leu44-Asn114 |
| 蛋白编号 | P42830 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM Citrate,8% Trehalose,4% Mannitol,50mM NaCl,0.05% Tween 80,pH 5.0. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 7.95 KDa |
| SMILES Code | NONE |
| 别名 | 重组人CXCL5蛋白(E.coli, tag free) ;Recombinant Human CXCL5; C-X-C Motif Chemokine 5; ENA-78 (1-78); Epithelial-Derived Neutrophil-Activating Protein 78; Neutrophil-Activating Peptide ENA-78; Small-Inducible Cytokine B5; ENA-78 (8-78); ENA-78 (9-78); CXCL5; ENA78; SCYB5 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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