Recombinant Human CST3是来自人类的重组蛋白，在HEK293人源细胞中表达，为无标签形式。该蛋白即半胱氨酸蛋白酶抑制剂C，属于半胱氨酸蛋白酶抑制剂超家族第2类成员，广泛存在于人体组织和体液中，常用作肾功能生物标志物，可抑制多种半胱氨酸蛋白酶，参与调节酶活性，还与心血管疾病及阿尔茨海默病等脑部疾病相关。
Human CST3 (Mammalian, HEK293)/人CST3蛋白(Tag free, HEK293) 化学结构 CAS号：N/A
Human CST3 (Mammalian, HEK293)/人CST3蛋白(Tag free, HEK293) 3D分子结构 CAS号：N/A
Human CST3 (Mammalian, HEK293)/人CST3蛋白(Tag free, HEK293) 质控信息
Human CST3 (Mammalian, HEK293)/人CST3蛋白(Tag free, HEK293) 生物活性
描述
Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.
Lyophilized from a 0.2 μm filtered solution of 10mM PB, 200mM NaCl, pH 6.5.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human CST3 (Mammalian, HEK293)/人CST3蛋白(Tag free, HEK293) 技术信息
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