货号:A2924920
同义名:
重组人CST3蛋白(C-6His, HEK293)
/ Recombinant Human CST3 (C-6His, HEK293); Cystatin-C
Recombinant Human CST3 (C-6His, HEK293) 是人源的重组Cystatin C蛋白,在HEK293细胞中表达,带有C端6×His标签。该蛋白属于半胱氨酸蛋白酶抑制剂超家族第2组成员,广泛存在于人体组织和体液中,常用作肾功能生物标志物,可抑制多种半胱氨酸蛋白酶,如木瓜蛋白酶及组织蛋白酶B、H、K、L和S,参与调节酶活性,与心血管疾病发生发展及阿尔茨海默病等脑部淀粉样病变相关。


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| 描述 | Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Ser27-Ala146 |
| 蛋白编号 | P01034 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 液体 |
| 剂型描述 | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 0.01% Tween 80, 1mM EDTA, 50% Glycerol, pH 8.0. |
| 复溶 | 如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 14.4 KDa |
| SMILES Code | NONE |
| 别名 | 重组人CST3蛋白(C-6His, HEK293) ;Recombinant Human CST3 (C-6His, HEK293); Cystatin-C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin; CST3 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |
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