Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293)
{[allProObj[0].p_purity_real_show]}
货号：A2924506同义名：
重组人CLEC10A蛋白(C-6His, HEK293)
/ Recombinant Human CLEC10A (C-6His, HEK293); C-Type Lectin Domain Family 10 Member A
Recombinant Human CLEC10A (C-6His, HEK293) 是人源 CLEC10A 蛋白，在 HEK293 细胞中表达，带有 C 端 6×His 标签。该蛋白是 II 型跨膜 C 型凝集素，主要表达于未成熟髓系树突状细胞和耐受性巨噬细胞，可识别并结合末端非唾液酸化 GalNAc 糖基分子，也结合马尔堡和埃博拉病毒包膜糖蛋白，参与自身异常及病原体分子的识别。
Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293) 化学结构 CAS号：N/A
Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293) 3D分子结构 CAS号：N/A
Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293) 质控信息
Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293) 生物活性
描述
C-Type Lectin Domain Family 10 Member A (CLEC10A) is a type II transmembrane C-type lectin that is expressed on immature myleloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10A/MGL binds and internalizes molecules with terminal nonsialylated GalNAc carbohydrates such as the Tn carcinoma antigen. CLEC10A/MGL also binds the GP envelope glycoprotein on Marburg and Ebola viruses and enhances viral entry and infectivity. It constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. CLEC10A is thought to participate in the recognition of molecules from both altered self and pathogens due to its monosaccharide specificity for Gal and N-acetylgalactosamine (GalNAc). Human and rat carry a single gene for CLEC10A/MGL, while mouse has two closely related MGL1 and MGL2 genes.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293) 技术信息
CAS号
N/A
分子量
29.8 KDa
SMILES Code
NONE
别名
重组人CLEC10A蛋白(C-6His, HEK293)
;Recombinant Human CLEC10A (C-6His, HEK293); C-Type Lectin Domain Family 10 Member A; C-Type Lectin Superfamily Member 14; Macrophage Lectin 2; CD301; CLEC10A; CLECSF13; CLECSF14; HML
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
最近浏览的产品
Tags:
Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293)
|Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293)
| 重组人CLEC10A蛋白(C-6His, HEK293)
| Recombinant Human CLEC10A (C-6His, HEK293)
| C-Type Lectin Domain Family 10 Member A
| C-Type Lectin Superfamily Member 14
| Macrophage Lectin 2
| CD301
| CLEC10A
| CLECSF13
| CLECSF14
| HML
| N/A
| Pattern Recognition Receptors
| Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293) 纯度/质量文件
| Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293) 生物活性
| Human CLEC10A (C-6His, HEK293)/人CLEC10A蛋白(C-6His, HEK293) 技术信息
搜索
