货号:A2924418
同义名:
重组人CEACAM1蛋白(C-6His, HEK293)
/ Recombinant Human CEACAM1 (C-6His, HEK293); Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1
Recombinant Human CEACAM1 (C-6His, HEK293) 是人源的重组蛋白,在HEK293细胞中表达,带有C端6×His标签。该蛋白是癌胚抗原相关细胞粘附分子1(CEACAM1),属于免疫球蛋白超家族,最初在肝胆管中被发现,广泛表达于白细胞、上皮及内皮细胞,介导同源及异源细胞粘附,参与组织三维结构形成、血管生成、凋亡、肿瘤抑制、转移及先天与适应性免疫调节。


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| 描述 | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a member of the Carcinoembryonic Antigen (CEA) family, which belongs to the immunoglobulin superfamily. CEACAM1 is originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it is found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM1 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, CEACAM1 plays a important role in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Gln35-Gly428 |
| 蛋白编号 | P13688 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 44.33 KDa |
| SMILES Code | NONE |
| 别名 | 重组人CEACAM1蛋白(C-6His, HEK293) ;Recombinant Human CEACAM1 (C-6His, HEK293); Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1; Biliary Glycoprotein 1; BGP-1; CD66a; CEACAM1; BGP; BGP1 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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