货号:A2924481
同义名:
重组人CD98蛋白(C-6His, HEK293)
/ Recombinant Human CD98 (C-6His, HEK293); 4F2 Cell-Surface Antigen Heavy Chain
Recombinant Human CD98 (C-6His, HEK293) 是人源CD98蛋白,在HEK293细胞中表达,带有C端6×His标签。该蛋白属于SLC3A转运蛋白家族,是一种单次跨膜I型膜蛋白,广泛表达于多种组织,尤其在肾脏、胎盘和睾丸中高表达。其重链与轻链共同介导氨基酸转运、整合素信号及T细胞共刺激等功能,参与B细胞增殖和病毒膜融合。


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| 描述 | CD98 is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2/MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. It consists of an 85 kDa glycosylated type II transmembrane heavy chain and a 40-50 kDa non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5, 6, 7, 8, 10, or 11) and is required for the cell surface expression and amino acid transport function of the light chains. It is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. It also mediates integrin signaling, T cell costimulation, B cell proliferation, and viral fusion with cell membranes. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His |
| 蛋白表达区间 | Arg206-Ala630 |
| 蛋白编号 | P08195 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Threhalose, pH 7.2. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 47.89 KDa |
| SMILES Code | NONE |
| 别名 | 重组人CD98蛋白(C-6His, HEK293) ;Recombinant Human CD98 (C-6His, HEK293); 4F2 Cell-Surface Antigen Heavy Chain; 4F2hc; 4F2 Heavy Chain Antigen; Lymphocyte Activation Antigen 4F2 Large Subunit; CD98; SLC3A2; MDU1 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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