Recombinant Human CD7 (C-6His, HEK293)是人源CD7蛋白，在HEK293细胞中表达，带有C端6×His标签。该蛋白属于免疫球蛋白超家族，是一种单次跨膜I型膜蛋白，主要表达于T淋巴细胞、NK细胞、前B淋巴细胞及多能造血干细胞，参与T细胞与B细胞间相互作用、T细胞和NK细胞活化及细胞因子产生，功能与PIK3R1和SECTM1存在关联，免疫作用机制尚未完全明确。
Human CD7 (C-6His, HEK293)/人CD7蛋白(C-6His, HEK293) 化学结构 CAS号：N/A
Human CD7 (C-6His, HEK293)/人CD7蛋白(C-6His, HEK293) 3D分子结构 CAS号：N/A
Human CD7 (C-6His, HEK293)/人CD7蛋白(C-6His, HEK293) 质控信息
Human CD7 (C-6His, HEK293)/人CD7蛋白(C-6His, HEK293) 生物活性
描述
T-Cell Antigen CD7 is a single-pass type I membrane protein that that belongs to the the immunoglobulin superfamily. Human CD7 is synthesized as a 240 amino acid precursor that contains a 25 amino acid signal sequence and a 215 amino acid mature chain with a Ig-like (immunoglobulin-like) domain. CD7 is normally expressed on all T-lymphocytes, NK-cells, pre-B lymphocytes and pleuripotent hematopoietic stem cells. CD7 plays an essential role in T-cell interactions, T-cell/B-cell interaction during early lymphoid development, T- and NK-cell activation and cytokine production. CD7 has been shown to interact with PIK3R1and SECTM1. However, the function of the CD7 protein in the immune system is still largely unknown.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human CD7 (C-6His, HEK293)/人CD7蛋白(C-6His, HEK293) 技术信息
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