货号:A2925485
同义名:
重组人CD27L蛋白(C-mFc, HEK293)
/ Recombinant Human CD27L (C-mFc, HEK293); CD70 antigen
Recombinant Human CD27L (C-mFc, HEK293) 是人源CD27配体蛋白,在HEK293人源细胞中表达,带有C端mFc标签。该蛋白为64%与人、小鼠和大鼠同源的II型跨膜糖蛋白,属于TNF配体家族,是TNFRSF27/CD27的配体,主要表达于活化的T和B淋巴细胞表面,可促进T细胞增殖与活化,增强细胞毒性T细胞生成,并参与调节B细胞活化及NK细胞功能。


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| 描述 | CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-mFc |
| 蛋白表达区间 | Gln45-Pro193 |
| 蛋白编号 | P32970 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 43 KDa |
| SMILES Code | NONE |
| 别名 | 重组人CD27L蛋白(C-mFc, HEK293) ;Recombinant Human CD27L (C-mFc, HEK293); CD70 antigen; CD70; CD27 ligand; Tumor necrosis factor ligand superfamily member 7; CD27LG; TNFSF7; CD27L |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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