Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293)
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货号：A2924730同义名：
重组人CD16b蛋白(C-Fc, HEK293)
/ Recombinant Human CD16b (C-Fc, HEK293); Low affinity immunoglobulin gamma Fc region receptor III-B
Recombinant Human CD16b (C-Fc, HEK293)是人类来源的重组蛋白，在HEK293人源细胞中表达，带有C-Fc标签。该蛋白又称FCGR3B，是低亲和力免疫球蛋白γFc区受体III-B，属于含两个Ig样C2结构域的GPI锚定膜蛋白，主要表达于外周血粒细胞和活化嗜酸性粒细胞，可结合INPP5D/SHIP1，参与调控中性粒细胞炎症募集与活化，并可能在外周循环中捕获免疫复合物而不激活中性粒细胞。
Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293) 化学结构 CAS号：N/A
Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293) 3D分子结构 CAS号：N/A
Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293) 质控信息
Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293) 生物活性
描述
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293) 技术信息
CAS号
N/A
分子量
48.8 KDa
SMILES Code
NONE
别名
重组人CD16b蛋白(C-Fc, HEK293)
;Recombinant Human CD16b (C-Fc, HEK293); Low affinity immunoglobulin gamma Fc region receptor III-B; Fc-gamma RIII-beta; FcR-10; IgG Fc receptor III-1; FCG3; FCGR3; CD16b; FCGR3B
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293)
|Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293)
| 重组人CD16b蛋白(C-Fc, HEK293)
| Recombinant Human CD16b (C-Fc, HEK293)
| Low affinity immunoglobulin gamma Fc region receptor III-B
| Fc-gamma RIII-beta
| FcR-10
| IgG Fc receptor III-1
| FCG3
| FCGR3
| CD16b
| FCGR3B
| N/A
| Epithelial cell CD Proteins
| Platelet CD Proteins
| B Cell CD Proteins
| Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293) 纯度/质量文件
| Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293) 生物活性
| Human CD16b (C-Fc, HEK293)/人CD16b蛋白(C-Fc, HEK293) 技术信息
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