Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+, Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small, highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes, but it is always found intracellularly.
Lyophilized from a 0.2 μm filtered solution of 50mM NH4HCO3, pH 8.0.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human CALM1/人CALM1蛋白(E.coli, tag free) 技术信息
CAS号
N/A
分子量
16.8 KDa
SMILES Code
NONE
别名
重组人CALM1蛋白(E.coli, tag free)
;Recombinant Human CALM1; Calmodulin; CaM; CALM1; CALM; CAM; CAM1; CALM2; CAM2; CAMB; CALM3; CALML2; CAM3; CAMC; CAMIII
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human CALM1/人CALM1蛋白(E.coli, tag free)
|Human CALM1/人CALM1蛋白(E.coli, tag free)
| 重组人CALM1蛋白(E.coli, tag free)
| Recombinant Human CALM1
| Calmodulin
| CaM
| CALM1
| CALM
| CAM
| CAM1
| CALM2
| CAM2
| CAMB
| CALM3
| CALML2
| CAM3
| CAMC
| CAMIII
| N/A
| Other Target Proteins
| Human CALM1/人CALM1蛋白(E.coli, tag free) 纯度/质量文件
| Human CALM1/人CALM1蛋白(E.coli, tag free) 生物活性
| Human CALM1/人CALM1蛋白(E.coli, tag free) 技术信息
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