Human CALCA (C-6His,Mammalian)/人CALCA蛋白(HEK293, C-6His)
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货号：A2900697同义名：
重组人CALCA蛋白(HEK293, C-6His)
/ Recombinant Human CALCA (C-6His,Mammalian); Calcitonin
Recombinant Human CALCA (C-6His,Mammalian) 是人源蛋白，在哺乳动物细胞中表达，带有C端6×His标签。该蛋白为降钙素前体，可裂解为降钙素与Katacalcin两条链，其中Katacalcin为强效降血钙肽，降钙素为32个氨基酸组成的线性多肽激素，能降低血钙与血磷水平，通过促进骨矿化抑制甲状旁腺激素作用，调节钙稳态。
Human CALCA (C-6His,Mammalian)/人CALCA蛋白(HEK293, C-6His) 化学结构 CAS号：N/A
Human CALCA (C-6His,Mammalian)/人CALCA蛋白(HEK293, C-6His) 3D分子结构 CAS号：N/A
Human CALCA (C-6His,Mammalian)/人CALCA蛋白(HEK293, C-6His) 质控信息
Human CALCA (C-6His,Mammalian)/人CALCA蛋白(HEK293, C-6His) 生物活性
描述
Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human CALCA (C-6His,Mammalian)/人CALCA蛋白(HEK293, C-6His) 技术信息
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