货号:A2926071
同义名:
重组人CALCA蛋白(C-6His, E.coli)
/ Recombinant Human CALCA (C-6His, E.coli); Calcitonin
Recombinant Human CALCA (C-6His, E.coli) 是人源降钙素α蛋白,在大肠杆菌中表达,带有C端6×His标签。该蛋白属于分泌型蛋白,属于降钙素家族,可被切割为降钙素与Katacalcin两条链,其中Katacalcin为强效降血钙多肽,降钙素为32个氨基酸组成的线性多肽激素,能降低血钙和血磷水平,通过促进骨钙沉积拮抗甲状旁腺激素作用,主要用于调节钙稳态相关研究。


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| 描述 | Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. |
| 蛋白种属 | Human |
| 表达系统 | E.coli |
| 标签 | C-6His |
| 蛋白表达区间 | Tyr58-Asn141 |
| 蛋白编号 | P01258 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 液体 |
| 剂型描述 | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 50% Glycerol, pH 7.4. |
| 复溶 | 如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 10.5 KDa |
| SMILES Code | NONE |
| 别名 | 重组人CALCA蛋白(C-6His, E.coli) ;Recombinant Human CALCA (C-6His, E.coli); Calcitonin; Katacalcin; Calcitonin Carboxyl-Terminal Peptide; CCP; PDN-21; CALCA; CALC1 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |
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