Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293)
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货号：A2924496同义名：
重组人BTN3A1蛋白(C-Fc, HEK293)
/ Recombinant Human BTN3A1 (C-Fc, HEK293); Butyrophilin subfamily 3 member A1
Recombinant Human BTN3A1 (C-Fc, HEK293)是人类Butyrophilin Subfamily 3 Member A1蛋白，在HEK293人源细胞中表达，带有C端Fc标签。该蛋白属于Ig超家族的I型跨膜糖蛋白，广泛表达于免疫细胞，其结构与B7共刺激分子相似，参与识别应激细胞并激活Vγ9Vδ2 T细胞，有助于增强抗肿瘤免疫应答。
Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293) 化学结构 CAS号：N/A
Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293) 3D分子结构 CAS号：N/A
Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293) 质控信息
Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293) 生物活性
描述
Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293) 技术信息
CAS号
N/A
分子量
50.8 KDa
SMILES Code
NONE
别名
重组人BTN3A1蛋白(C-Fc, HEK293)
;Recombinant Human BTN3A1 (C-Fc, HEK293); Butyrophilin subfamily 3 member A1; CD277; BTN3A1; BTF5
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293)
|Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293)
| 重组人BTN3A1蛋白(C-Fc, HEK293)
| Recombinant Human BTN3A1 (C-Fc, HEK293)
| Butyrophilin subfamily 3 member A1
| CD277
| BTN3A1
| BTF5
| N/A
| Butyrophilins
| Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293) 纯度/质量文件
| Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293) 生物活性
| Human BTN3A1 (C-Fc, HEK293)/人BTN3A1蛋白(C-Fc, HEK293) 技术信息
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